Hmm, from the ones I have?
Super Mario 64 DS -If you haven't played the original this is a great time to start! And the mini games are amazingly addictive! Show off those mini games to your friends and it should interest them!
Yoshi Touch and Go - I don't recommend this one, but it's sometimes fun in bursts.
Mario Kart DS - Always fun with friends, or even alone, the added bots to the multiplayer games is a great plus! Online raises the replayability tons!
Animal Crossing: Wild World - This a great game! So much potential with the online addition. Although the experience can be ruined if you have hacker friends. XD. It's also fun to get on message boards to sell stuff or whatever.
Castlevania: Dawn of Sorrow - Seriously, Aria of Sorrow was the first game to get me hooked onto the castlevania series. The main character was just so awsome! So this sequel was flippin amazing! One of the best platformers on the DS! Hard to find now though, sadly.
Metroid Prime: Hunters - Now this game is THE game that shows how well fps's can work on the DS. Might not be your kind of genre, but who knows, maybe this game might spark your interest. The multiplayer aspect is more focused upon, and it's great! Best online game out right now!(until april..because of pokemon!

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Pokemon Trozei - A fun little puzzle game with a pretty addicting formula. Might get old, but it's still fun to play in bursts. Probably not as fun as tetris, but it's still a good puzzle game. Gotta trozei'em all!
Tony Hawk American Sk8land - This game is pretty awsome. The graphics are sweet. Cellshading is a good look for the DS. The online part is really good and it's pretty in-depth. There are some cool little extra's like using your own voice recording when you do good or bad, and designing your board, and even making your own graffiti.
Trauma Center: Under the Knife - This game is one of the most innovative titles. It just works so well! It's also one of the hardest games ever! Which is good because games seem like they're getting too easy. Definitly cool to show your friends. There's even partial nudity.
Super Monkey Ball: Touch and Roll - The Monkey ball series is great. The mini games are awsome too. There's bowling, mini golf, air hockey, and more. Air hockey is by far the coolest mini game on the DS right now.
Cooking mama - It's fun for a while.. Hehe.
Elite beat agents - One of the best music games EVER! Easy to learn, hard to master. This is probably a must get game! Heck it even won IGN's DS Game of the Year.
Well that's about it. Maybe I'll make a post later saying what games i'm looking forward to get.